Malignant Transformation of Heterotopic Pancreatic Tissue in a Patient with BRCA2 Mutation

Background: Malignant transformation of heterotopic pancreatic tissue is a rare entity with only several case reports published in the scientific literature. Adjuvant chemotherapy following oncological resection for lesions nodal metastasis has not been well described and there are no guidelines available to guide management these patients. Case Presentation: We present gastric carcinoma young patient breast cancer gene (BRCA) 2 mutation. He had undergone laparoscopic wedge lesion initially thought be gastrointestinal stroma tumor. Given involvement margins, underwent distal gastrectomy lymph clearance. One out 33 harvested nodes harboured micrometastasis while main specimen did have any residual malignancy. Following histological diagnosis, he received an adjuvant regime akin that prescribed locally advanced adenocarcinoma good response. This is, our knowledge, also first such report BRCA2 Conclusions: Pre-operative diagnostic confirmation challenging endoscopic procedures pose significant false negatives. Reports limited regarding therapies. would recommend regimen similar primary patients found metastasis.